Cognitive & Neurological
DSIP
A delta sleep-inducing peptide studied to support deeper, more restorative rest and calmer nights
from $249/mo

What it is
A considered protocol.
DSIP, or delta sleep-inducing peptide, is a naturally occurring peptide studied for its role in the body's sleep and stress-regulation systems. It is used to support deep, restorative sleep and an easier transition into rest. At Orvo Health, it is compounded in a U.S. pharmacy and reviewed individually by a licensed provider.
How it works
The mechanism, plainly.
DSIP is a small peptide thought to interact with the systems that regulate sleep and stress signaling. Research is still emerging, and results vary between individuals.
Sleep signaling
DSIP is studied for its role in the deeper, slow-wave phases of the sleep cycle that support overnight recovery.
Stress modulation
It is also studied for its influence on stress-hormone pathways, which may support a calmer transition into rest.
Restorative rhythm
By supporting the body's own sleep architecture, it is studied for its role in helping you wake feeling more refreshed, though experiences differ.
Candidacy
A considered fit, not a funnel.
DSIP may suit adults seeking to support deeper, more consistent sleep under professional guidance.
- Adults wanting support for restorative sleep
- People with disrupted or restless sleep patterns
- Those seeking sleep support with physician oversight
- Anyone pregnant, breastfeeding, or planning pregnancy
- People with a current or prior cancer diagnosis
- Those with a seizure history, psychosis, or bipolar disorder
Your concierge support
A licensed clinician, matched to you.
Every peptide protocol is coordinated end to end by our licensed care team — reviewed individually, adjusted as you go, and never handed off to a rotating call center.
- 01Compounded medication
- Prepared by partner compounding pharmacies and shipped on a structured cadence.
- 02Dedicated provider
- Every interaction is coordinated directly by our licensed care team — not a rotating callcenter.
- 03Provider-directed dosing
- Titration and adjustments at every transition under expert clinical supervision.
- 04Direct message access
- Reach your provider directly between scheduled check-ins via your secure patient portal.
- 05Structured check-ins
- Cadenced reviews to keep your protocol and overall care plan calibrated to your response.
- 06Discreet direct delivery
- Temperature-controlled, unmarked packaging delivered direct to your door.
Clinical safety
No therapy is right for everyone.
Common side effects
Reported effects are typically mild and may include temporary injection-site irritation, morning grogginess, or headache. Your physician monitors your response and adjusts your plan as needed.
Who should not use it
DSIP is not appropriate during pregnancy, breastfeeding, or while planning pregnancy, with a current or prior cancer diagnosis, or with a history of seizures, psychosis, schizophrenia, bipolar disorder, or active suicidal ideation, and is used only with caution alongside SSRIs/SNRIs, benzodiazepines, stimulants, antipsychotics, mood stabilizers, MAOIs, or lithium. Your full medical history is reviewed before any prescription is authorized.
Orvo Health protocols are prepared by partner compounding pharmacies in the United States. Compounding pharmacies are regulated by both state boards and the FDA and have been part of American medicine since long before mass-manufactured drugs existed. The active ingredient is prepared per your protocol — supervised by your provider — and delivered direct to your door.
Begin assessment
DSIP begins with a short assessment.
A licensed provider reviews every order. If it's right for you, your protocol is compounded by a partner U.S. pharmacy and delivered discreetly to your door.